Alzheimer’s disease, a devastating neurodegenerative disorder, is closely linked to the accumulation of tau protein in the ...

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein ...

Scientists know that a build-up of specific proteins in the brain is associated with Alzheimer’s disease. However, by the time these proteins have become visible in brain scans, disease ...

Detecting toxic forms of tau before they weave into dense thickets of tangles could pave the way for earlier diagnosis and treatment of tauopathies, including Alzheimer’s disease. In the February 10 ...

June 15, 2021 — A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of ...

“While most Alzheimer’s research has focused on the buildup of amyloid beta and tau, the polyGR proteins we’ve found in Alzheimer’s brains were unexpected and completely different,” said ...

and tangled tau proteins. In healthy brains, tau binds to—and stabilizes—microtubules, which are hollow structures that play important roles in the structure, function, and development of the ...

Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts 02115, United States ...

and tangled tau proteins. In healthy brains, tau binds to—and stabilizes—microtubules, which are hollow structures that play important roles in the structure, function, and development of the ...

The variant causes a person's brain to accumulate beta amyloid and phosphorylated tau proteins, the hallmarks of Alzheimer's. When Whitney turned 60 and still had no symptoms, he assumed he didn't ...

In healthy individuals, the protein tau stabilizes the tubular building blocks (microtubules) that make up the long projections of the nerve cells. During the development of Alzheimer's disease, tau ...