DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers ...

A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

Herpesvirus infection may contribute to Alzheimer’s disease through transposable element activation and neuroinflammation.

DNA replication is the biological ... human cells suggests the role of this protein in maintaining the balance between mitochondrial transcription and replication.

Scientists know that a build-up of specific proteins in the brain is associated with Alzheimer’s disease. However, by the time these proteins have become visible in brain scans, disease ...

The topics covered range from control of genome stability and chromatin to metabolic plasticity during healthy aging, characterisation of long-lived model animals and molecular lessons from ...

Neurogeneticists have discovered a novel genetic mutation and associated buildup of toxic proteins in the brain -- a type of buildup distinct from amyloid or tau ... segment of DNA with a GGGAGA ...

The study was focused on analyzing tau, a protein in the brain that plays a key role in Alzheimer's. In people with the neurological disease, tau proteins undergo chemical changes, forming tangled ...

The variant causes a person's brain to accumulate beta amyloid and phosphorylated tau proteins, the hallmarks of Alzheimer's. When Whitney turned 60 and still had no symptoms, he assumed he didn't ...

This breakthrough was made possible by the development of a novel transgenic mouse model that replicates both tau and beta-amyloid pathologies. “Although both proteins accumulate in the brains ...

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological hallmarks of Alzheimer's—tau protein and beta ...

Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau proteins have been found in PDD, with intermediate changes for Aβ42 in non-demented PD. The authors investigated whether AD-related ...