Researchers at the University of Cologne reveal how the 1N4R tau isoform contributes to Alzheimer’s, paving the way for ...

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease. Using human induced pluripotent stem cells (iPSCs) ...

Scientists know that a build-up of specific proteins in the brain is associated with Alzheimer’s disease. However, by the time these proteins have become visible in brain scans, disease ...

June 15, 2021 — A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of ...

The study was focused on analyzing tau, a protein in the brain that plays a key role in Alzheimer's. In people with the neurological disease, tau proteins undergo chemical changes, forming tangled ...

This breakthrough was made possible by the development of a novel transgenic mouse model that replicates both tau and beta-amyloid pathologies. “Although both proteins accumulate in the brains ...

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological hallmarks of Alzheimer's—tau protein and beta ...