Researchers develop early Alzheimers diagnostic method using tau protein analysis Advancements in Alzheimers detection reveal early risks through tau protein mutations ...
Scientists have identified a biomarker for Alzheimer's that may help doctors spot the early signs of protein buildup in the ...
Alzheimer’s disease, a devastating neurodegenerative disorder, is closely linked to the accumulation of tau protein in the ...
Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the ...
Herpesvirus infection may contribute to Alzheimer’s disease through transposable element activation and neuroinflammation.
Abnormal iron accumulation can activate various kinases such as glycogen synthase kinase-3β, cyclin-dependent kinase 5, and mitogen-activated protein kinase, leading to abnormal phosphorylation of tau ...
can identify clumping-prone tau proteins and help initiate further diagnostics and early treatment. In particular, the two new phosphorylation sites, p-tau-262 and p-tau-356, can accurately inform the ...
Tau protein (MAPT) is classified as a microtubule-associated protein (MAP) and is believed to regulate the axonal microtubule arrangement. It belongs to the tau/MAP2/MAP4 family of MAPs that have a ...
this protein goes awry and develops into NFTs. Tau can become phosphorylated, meaning that phosphate groups are added to it. This is normal, but in the case of Alzheimer’s, the phosphorylation ...