Tau proteins with cysteine groups bearing thiol groups (S) undergo chemical changes under oxidative stress to form disulfide bonds, making a toxic mutant of the tau protein that can aggregate.

A recent study by the University of Cologne has illuminated a specific tau protein's role in the progression of Alzheimer's ...

A new study has revealed for the first time the molecular structure ... proteins in the brain, including two proteins in particular that are associated with Alzheimer's: beta-amyloid and tau.

Researchers have identified a specific form of the tau protein that is responsible for mediating the toxicity of harmful protein clumps in human neurons and thus represents a target for future treatme ...

Current therapies mainly focus on blocking just one of the toxic proteins associated ... Published in Molecular Psychiatry (Nature group), the findings reveal that tau accumulation in the ...

Tau protein is a microtubule-associated protein (MAP) known to stabilize the internal structure of neurons ... Medical Research Council Laboratory of Molecular Biology and other institutes ...