Scientists from the University of Cologne identified the 1N4R tau isoform as a key contributor to neuronal dysfunction in ...

"One part of it folds into a hairpin structure only in the 4R tau." Within the hairpin, he explained, is a sticky segment called PHF6 that can bind and stack up other tau proteins into large ...

Scientists have identified a biomarker for Alzheimer's that may help doctors spot the early signs of protein buildup in the ...

Tau protein is a microtubule-associated protein (MAP) known to stabilize the internal structure of neurons, binding to microtubules. These are microscopic tubular structures that support the ...

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease.

Rather than looking for amyloid-beta plaques like many other Alzheimer's tests, this one hunts for tiny clumps of tau protein, which are more often associated with cognitive decline. The ...

and tangled tau proteins. In healthy brains, tau binds to—and stabilizes—microtubules, which are hollow structures that play important roles in the structure, function, and development of the ...

and tangled tau proteins. In healthy brains, tau binds to—and stabilizes—microtubules, which are hollow structures that play important roles in the structure, function, and development of the ...

Mar. 30, 2022 — In the course of Alzheimer's disease, two proteins called 'amyloid' and 'tau' accumulate in the brain. A new study with more than 200 participants now provides insights into the ...

Researchers from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) have found that tau protein and beta-amyloid – two pathological hallmarks of Alzheimer’s disease – ...