Elevated p-eIF2α, and its proper sensing by the decameric eIF2B complex, are essential to balance translation. Knockdown or mutation of eIF2Bα and eIF2Bδ, two eIF2B subunits responsible for sensing ...

The central nervous system candidate is eIF2B activator ABBV-CLS-7262, in a multiple dose study to assess its safety and pharmacokinetics in patients with amyotrophic lateral sclerosis ...

both eIF2B agonists, in failing to slow disease progression in the study. There may be a silver lining, however, as two of them – pridopidine and CNM-Au8 – showed signs of activity on measure ...

CEL-SCI Corporation announced new data has been published from its prior Phase 3 study of Multikine* (Leukocyte Interleukin, Injection) in newly diagnosed, treatment naïve, resectable, locally ...

After hours: March 21 at 4:38:17 p.m. EDT Loading Chart for DNLI ...