Alzheimer’s disease, a devastating neurodegenerative disorder, is closely linked to the accumulation of tau protein in the ...

In addition to being a runnable CLI tool, D2 can also be used to produce diagrams from Go programs. For examples, see ./docs/examples/lib. This blog post also demos a complete, runnable example of ...

Scientists know that a build-up of specific proteins in the brain is associated with Alzheimer’s disease. However, by the time these proteins have become visible in brain scans, disease ...

June 15, 2021 — A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of ...

and tangled tau proteins. In healthy brains, tau binds to—and stabilizes—microtubules, which are hollow structures that play important roles in the structure, function, and development of the ...

In 2019, the team engineered protein microtubules to respond instead to gradients of light, which allowed the researchers to shine specific patterns of light on a clump of microtubules and induce ...

This breakthrough was made possible by the development of a novel transgenic mouse model that replicates both tau and beta-amyloid pathologies. “Although both proteins accumulate in the brains ...

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological hallmarks of Alzheimer's—tau protein and beta ...

Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau proteins have been found in PDD, with intermediate changes for Aβ42 in non-demented PD. The authors investigated whether AD-related ...

"This research shows beyond doubt that organic biomolecules, such as proteins like collagen, appear to be present in some fossils," says University of Liverpool materials scientist Steve Taylor. "Our ...