A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease. Using human induced pluripotent stem cells (iPSCs) ...

Scientists know that a build-up of specific proteins in the brain is associated with Alzheimer’s disease. However, by the time these proteins have become visible in brain scans, disease ...

June 15, 2021 — A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of ...

The best of New York for free. Sign up for our email to enjoy New York without spending a thing (as well as some options when you’re feeling flush). Our newsletter hand-delivers the best bits to ...

The study was focused on analyzing tau, a protein in the brain that plays a key role in Alzheimer's. In people with the neurological disease, tau proteins undergo chemical changes, forming tangled ...

This breakthrough was made possible by the development of a novel transgenic mouse model that replicates both tau and beta-amyloid pathologies. “Although both proteins accumulate in the brains ...

A research team from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has discovered that the two key pathological hallmarks of Alzheimer's—tau protein and beta ...

Altered cerebrospinal fluid (CSF) levels of amyloid-β (Aβ) and tau proteins have been found in PDD, with intermediate changes for Aβ42 in non-demented PD. The authors investigated whether AD-related ...

Antibody epitopes in the mid-region of tau make the assay sensitive to normal and phosphorylated tau, including most of the known protein isoforms. Thereafter, the capture beads were resuspended with ...

Tau protein (MAPT) is classified as a microtubule-associated protein (MAP) and is believed to regulate the axonal microtubule arrangement. It belongs to the tau/MAP2/MAP4 family of MAPs that have a ...