Neurofibrillary tangles (NFTs) are a hallmark of Alzheimer’s disease, formed by the accumulation of tau protein into fibrillar structures. These tangles, composed of paired helical filaments and ...

Researchers have developed a test that spots early signs of Alzheimer's disease. Rather than looking for amyloid-beta plaques ...

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease.

Researchers develop early Alzheimers diagnostic method using tau protein analysis Advancements in Alzheimers detection reveal early risks through tau protein mutations ...

In the January 15 Neuron, researchers led by Seong Kang at Emory University, Atlanta, and Keqiang Ye at Shenzhen Institutes of Advanced Technology, China, report that ApoE3Ch also binds tau directly ...

They found a core element of the protein that plays a primary role in tangle formation: an amino acid sequence called tau258-368. This sequence is identifiable in "clumping-prone" tau proteins up ...