They also say that their graphene grid method could be used to determine the structures of other small and unstable proteins—including the amyloid-beta peptide that builds up in the brain in ...

Researchers from Osaka University found that peristaltic pump flow mechanically breaks supersaturation to induce amyloid ...

The research team, coordinated by pharma startup Cortexyme, did not claim to have discovered definitive evidence of Alzheimer ...

The factor that tips you over the edge from being at risk for a disease to actually developing the disease is not always ...

He had been working in the realm of wet lab experimental biochemistry when he decided to ... In its monomeric form, amyloid-β begins as an intrinsically disordered protein; however, it can assemble ...

Misfolded proteins (also called toxic conformations) are typically insoluble, and they tend to form long linear or fibrillar aggregates known as amyloid deposits. But how can a protein change so ...

Jr., "The carboxy terminus of the b amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease," Biochemistry, 32:4693-7, 1993. (Cited ...

This process involves the formation of amyloid fibrils, crystal-like collections of misfolded proteins that clump together ...

protein, amyloid-beta. Pathological forms of amyloid-beta start appearing in a patient’s blood 15–20 years before AD symptoms occur. The scientists investigated how early the test could be effective ...

Researchers at the University of Cologne have identified a specific form of the tau protein that is responsible for mediating the toxicity of harmful protein clumps in human neurons and thus represent ...