Neurofibrillary tangles (NFTs) are a hallmark of Alzheimer’s disease, formed by the accumulation of tau protein into fibrillar structures. These tangles, composed of paired helical filaments and ...

Researchers have developed a test that spots early signs of Alzheimer's disease. Rather than looking for amyloid-beta plaques ...

A new biomarker test can detect early-stage tau protein clumping up to a decade before it appears on brain scans, improving ...

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer's disease.

Researchers develop early Alzheimers diagnostic method using tau protein analysis Advancements in Alzheimers detection reveal early risks through tau protein mutations ...

Mar. 30, 2022 — In the course of Alzheimer's disease, two proteins called 'amyloid' and 'tau' accumulate in the brain. A new study with more than 200 participants now provides insights into the ...

Researchers from the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) have found that tau protein and beta-amyloid – two pathological hallmarks of Alzheimer’s disease – ...

They found a core element of the protein that plays a primary role in tangle formation: an amino acid sequence called tau258-368. This sequence is identifiable in "clumping-prone" tau proteins up ...