Protein kinase C in Wnt signaling: implications in cancer ... - PubMed
PKC is one of the key targets of noncanonical Wnt signaling, particularly in the Wnt/Ca(2+) pathway. Recently, data have implicated components of noncanonical Wnt/Ca(2+) and …
Modulating PKCα Activity to Target Wnt/β-Catenin Signaling in …
May 18, 2019 · Inactivating mutations of the tumor suppressor Adenomatosis Polyposis Coli (APC), which are found in familial adenomatosis polyposis and in 80% of sporadic colorectal …
Xihuang pills targeting the Warburg effect through inhibition of …
XHP treatment downregulated Wnt signaling pathway-related genes, including CCND2, PRKCG, and CCN4. Moreover, XHP effectively inhibited glucose uptake and lactate production, leading …
Wnt Target genes | The Wnt Homepage - Stanford University
Jan 1, 2025 · This is a list of target genes of Wnt/beta-catenin signaling. Suggestions for additions are welcome. There are a separate lists of papers on expression profiling (micro-arrays) on …
Mtf2-PRC2 control of canonical Wnt signaling is required for
May 1, 2018 · Gene regulatory network (GRN) analysis demonstrated Mtf2 directly regulates Wnt signaling in erythroblasts, leading to activated canonical Wnt signaling in Mtf2-deficient …
Pan-Cancer Study on Protein Kinase C Family as a Potential …
High PRKCG improved PAAD and SKCM patients’ survival and reduced KIRC, PCPG, and UVM patients’ survival. Furthermore, elevated PRKCH was associated with better survival in ACC, …
Wnt signaling pathway-derived score for predicting therapeutic ...
The function of Wnt is most common in embryogenesis and tumorigenesis, but previous literature has only described the carcinogenic effect of Wnt and rarely investigated its predictive ability. …
PRKCG Gene - GeneCards | KPCG Protein | KPCG Antibody
Dec 25, 2024 · PRKCG (Protein Kinase C Gamma) is a Protein Coding gene. Diseases associated with PRKCG include Spinocerebellar Ataxia 14 and Retinitis Pigmentosa 59. …
PKCγ promotes axonal remodeling in the cortico-spinal tract
Nov 19, 2019 · In this study, we deployed loss and gain of function strategies in N2a cells and primary cortical neurons in vitro, and demonstrated that PKCγ is not only important but …
Protein kinase C and cancer: what we know and what we do not
Dec 16, 2013 · Protein kinase C (PKC), a prototypical class of serine/threonine kinases, exemplifies specific signaling molecules that link multiple cellular processes to cancer.
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