Dec 25, 2024 · PDK1 (Pyruvate Dehydrogenase Kinase 1) is a Protein Coding gene. Diseases associated with PDK1 include Pyruvate Dehydrogenase E3-Binding Protein Deficiency and …

Pyruvate dehydrogenase kinase (also pyruvate dehydrogenase complex kinase, PDC kinase, or PDK; EC 2.7.11.2) is a kinase enzyme which acts to inactivate the enzyme pyruvate …

This review seeks to elucidate the regulation of PDK activity in different species, mainly mammals, and the role of PDK inhibitors in preventing increased blood glucose, reducing injury caused …

Mar 7, 2024 · Our study uncovers pronounced genetic heterogeneity among PDK family members, coupled with discernible clinical characteristic. Significantly, the study establishes …

Sep 14, 2007 · Here, we show that they are direct regulators of the family of pyruvate dehydrogenase kinase (PDK) genes, whose products act as metabolic homeostats in sensing …

Jan 4, 2025 · Note: PDK1 (Gene ID: 5163) and PDPK1 (Gene ID: 5170) share the PDK1 symbol/alias in common. PDK1 is a widely used alternative name for 3-phosphoinositide …

Dec 25, 2024 · PDK2 (Pyruvate Dehydrogenase Kinase 2) is a Protein Coding gene. Diseases associated with PDK2 include Pyruvate Dehydrogenase E3-Binding Protein Deficiency and …

Gene ID: 5163, updated on 8-Feb-2025. Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of …

May 5, 2023 · The pyruvate dehydrogenase kinases (PDK; four genes: PDK1-4) are major regulatory subunits of the PDH complex, since phosphorylation of E1 catalytic subunit by PDK …

Apr 30, 2021 · Pyruvate dehydrogenase kinase (PDK) can regulate the catalytic activity of pyruvate decarboxylation oxidation via the mitochondrial pyruvate dehydrogenase complex, …