Comparative Analysis of the Flax Immune Receptors L6 and L7 ... - PubMed
NOD-like receptors (NLRs) are central components of the plant immune system. L6 is a Toll/interleukin-1 receptor (TIR) domain-containing NLR from flax (Linum usitatissimum) …
Frontiers | Structure and function of the TIR domain from the …
Dec 7, 2016 · The crystal structure of L6 TIR revealed an interface that is spatially distinct to the AE interface, involving the αD and αE helices and the βE strand. In L6 TIR, this region was …
Multiple functional self-association interfaces in plant TIR domains
Structure-based studies identified different TIR-domain dimerization interfaces required for signaling of the plant nucleotide-binding oligomerization domain-like receptors (NLRs) L6 from …
Two-faced TIRs trip the immune switch - PMC
In one of these papers, Zhang et al. report that, for TIR domains from Arabidopsis TNLs SNC1 and RPP1, and for the RPS4 and L6 TIR domains, both αD/αE and αA/αE interfaces …
Structural and Functional Analysis of a Plant Resistance Protein TIR ...
Mar 17, 2011 · In this study, we used the L6 protein as a model to characterize plant TIR domain signaling activity and mode of action. Mutational analysis showed that the TIR domain is …
Comparative Analysis of the Flax Immune Receptors L6 and L7 …
Jan 7, 2016 · NOD-like receptors (NLRs) are central components of the plant immune system. L6 is a Toll/interleukin-1 receptor (TIR) domain-containing NLR from flax (Linum usitatissimum) …
Crystallization, X-ray diffraction analysis and preliminary structure ...
In this study, the crystallization, X-ray diffraction analysis and preliminary structure determination of the TIR domain from the flax resistance protein L6 (L6TIR) are reported. Plate-like crystals …
Structure and Function of the TIR Domain from the Grape NLR ... - PubMed
Dec 8, 2016 · The N-terminal Toll/interleukin-1 receptor/resistance protein (TIR) domain has been shown to be both necessary and sufficient for defense signaling in the model plants flax and …
RCSB PDB - 3OZI: Crystal structure of the TIR domain from the …
Sep 25, 2010 · L6 is a TIR-NB-LRR resistance protein from flax (Linum usitatissimum) that confers resistance to the flax rust phytopathogenic fungus (Melampsora lini). We determine …
TIR domains of plant immune receptors are 2′,3′-cAMP ... - Cell Press
May 20, 2022 · Here, we show that plant TIR proteins, besides being NADases, act as 2′,3′-cAMP/cGMP synthetases by hydrolyzing RNA/DNA. Structural data show that a TIR domain …