Coated pits can concentrate large extracellular molecules that have different receptors responsible for the receptor-mediated endocytosis of ligands, e.g. low density lipoprotein, …

A coated pit is a structure on the plasma membrane that plays a role in receptor-mediated endocytosis by facilitating the internalization of macromolecules such as ligands, hormones, …

May 29, 2023 · Specialised regions of the cell membrane composed of pits coated with a bristle covering made of the protein clathrin. These pits are the entry route for macromolecules bound …

Jan 12, 2025 · Coated pits are specialized regions of the cell membrane that are involved in the internalization of extracellular material. They are composed of a protein coat, which underlies …

Aug 3, 2012 · The “canonical” coated pit is an invaginating structure, in which assembly of a curved clathrin lattice, linked by adaptors and other proteins to deformation of the underlying …

Recently, the study of endocytosis has extended into the living cell. The tracking of individual clathrin-coated pits and vesicles (CCPs and CCVs) has provided new insight into …

In this review we examine the canonical model of CME, highlight discrepancies with published experimental data and suggest future avenues of exploration while paying particular attention …

Sep 8, 2009 · Coated pits are small, rapidly forming structures that deform the underlying membrane by progressive recruitment of clathrin, adaptors, and other regulatory proteins. …

Feb 21, 2024 · Clathrin-coated pits are invaginations of the cell membrane characterized by a lattice-like coat composed of the protein clathrin. Clathrin molecules assemble into a …

Apr 29, 1999 · Diffusible transmembrane receptors or membrane-docking sites are thought to recruit AP-2 and clathrin to form a coated pit. But the new data indicate that coated-pit …