Jan 17, 2025 · New Insights Into Why Huntington’s Disease Has Delayed Onset. A highly-anticipated scientific paper has landed! This new work challenges current theories in Huntington’s disease research, uncovering how runaway CAG repeats erode cell identity in certain types of brain cells, leading to their death.

16 hours ago · A new paper led by researchers at the Massachusetts General Hospital and Harvard Medical School used CRISPR to work out which genes can influence how the genetic C-A-G repeat that causes Huntington’s disease (HD) can change over time. This exciting study helps us to better understand how HD works and uncovers some potential targets for therapies that could slow or halt the disease.

Jan 2, 2025 · As we wave goodbye to 2024, the HDBuzz team reflects on a year marked by significant progress, challenges, and hope. From breakthroughs at the lab bench, advancements in drug development, and both road bumps and triumphs in clinical trials, we have gained new insights into the workings of Huntington’s disease (HD), and made great strides towards finding medicines which might slow or halt ...

Jan 18, 2011 · HDBuzz is now live! Your source for Huntington’s disease research news, in plain language, written by scientists, for the global HD community.

Self-determination on the HD journey: the role of Advanced Care Planning. Advanced Care Planning is a tool that can allow people living with Huntington’s disease to compassionately engage with loved ones about their future care, taking thoughtful steps at their own pace while they’re able, to ensure their wishes are met.

Jan 20, 2025 · Glossary; blood-brain barrier A natural barrier, made from reinforcements to blood vessels, that prevents many chemicals from getting into the brain from the bloodstream ; CAG repeat The stretch of DNA at the beginning of the HD gene, which contains the sequence CAG repeated many times, and is abnormally long in people who will develop HD ; aggregate Lumps of protein that form inside cells in ...

May 1, 2024 · A new era for HDBuzz For over a decade HDBuzz has reported unbiased news about Huntington’s disease research and trials. As our beloved Ed and Jeff step back, Rachel, Sarah, and Leora look forward to upholding the HDBuzz mission.

Bringing HD Treatments to Market: The Role of Regulatory Oversight. Moving drugs from the lab bench to pharmacy shelves is no small task. In this article we delve into the role regulatory oversight plays in clinical trials and the approval of medicines for Huntington’s disease.

Hereditary Disease Foundation (HDF) conference 2024 – Day 3. Read our live tweet compilation from clinical trials and scientific research on Huntington’s disease from Day 3 of the 2024 HDF Milton Wexler Biennial Symposium #HDF2024

Nov 25, 2024 · We're proud to announce Jenny Lange as a 2024 HDBuzz Prize winner! Our brains are made up of many types of cells that play different roles in the changes caused by HD. This study dives into a star-shaped cell called astrocytes and their role in HD.