Dec 10, 2024 · Histologic type is hepatocellular carcinoma with grade G2 - G3: moderately to poorly differentiated. The tumor is confined to the liver and biliary and vascular margins are free of a tumor. Vascular invasion is present.

Hepatocellular carcinoma (HCC) is currently the sixth most common type of cancer with a high mortality rate and an increasing incidence worldwide. Its etiology is usually linked to environmental, dietary or life-style factors.

Hepatocellular carcinoma (HCC), a malignant tumor of hepatocytes, may exhibit any or all of the cytologic and/or architectural characteristics of hepatocellular differentiation, along with features of malignancy.

Core Tip: We summarize several new distinct histologic subtypes of hepatocellular carcinoma (HCC) and recurrent molecular alterations in HCC. Major histologic subtypes like macrotrabecular massive, fibrolamellar HCC, steatohepatitic HCC, scirrhous HCC, lymphoepithelioma-like HCC, and combined hepatocellaular-cholangiocarcinoma are discussed in ...

Hepatocellular carcinoma, abbreviated HCC, is the most common malignant primary liver tumour. It most often arises in the context of cirrhosis. Clinical: Serum AFP elevated - in approx. 50% of patients. [1] Treatments: RFA (radiofrequency ablation), ethanol ablation, liver …

Jun 12, 2023 · Histopathology. Hepatocellular carcinoma is a malignant tumor of the hepatocytes. Cytological features depend on the differentiation of hepatocytes. From well-differentiated to poorly differentiated HCC. The trabecular architectural pattern is the commonest.

Two of the common benign mass forming liver lesions are focal nodular hyperplasia (FNH) and hepatic adenoma. On biopsy, both can be challenging to distinguish from well-differentiated hepatocellular carcinoma.

Apr 27, 2021 · Recent advances in tumor genomics and transcriptomics have identified several recurrent somatic/genetic alterations that are closely related with histomorphological subtypes and have therefore, greatly improved our understanding of HCC pathogenesis.

Oct 10, 2022 · Hepatocellular carcinoma (HCC) is a primary malignant tumor of the liver consisting of neoplastic hepatocytes. Our understanding of this neoplasm has evolved in recent years and new histological variants and new molecular alterations have been described.

High-throughput sequencing technologies led to the identification of several molecular HCC subclasses that can be broadly grouped into 2 major subgroups, each characterized by specific morphological and phenotypical features.