
STK38L Gene - GeneCards | ST38L Protein | ST38L Antibody
Dec 25, 2024 · STK38L (Serine/Threonine Kinase 38 Like) is a Protein Coding gene. Diseases associated with STK38L include Bardet-Biedl Syndrome 18 and Ossification Of The Posterior Longitudinal Ligament Of Spine. Among its related pathways …
The Role of Mammalian STK38 in DNA Damage Response and …
High STK38L mRNA expression is associated with decreased overall patient survival in PDACs. STK38L contributes cell invasion and cytokinetic abnormalities of RASSF1A (Ras association (RalGDS/AF-6) domain family member 1)-depleted lung cancer cells by activating YAP [ 70 ].
STK38L serine/threonine kinase 38 like [ (human)] - National …
Feb 8, 2025 · Hypoxia-induced activation of NDR2 underlies brain metastases from Non-Small Cell Lung Cancer. TRIM27 cooperates with STK38L to inhibit ULK1-mediated autophagy and promote tumorigenesis. The results demonstrate that NDR2 is a reversible acetylated kinase regulated by SIRT1 and p300/CBP.
STK38L - Wikipedia
Serine/threonine-protein kinase 38-like is an enzyme that in humans is encoded by the STK38L gene. [5] [6]
Role of STK38L in atrial fibrillation-associated myocardial fibrosis ...
To explore the mechanism underlying myocardial fibrosis, we aimed to determine whether serine/threonine kinase 38 like (STK38L) contributes to the development of myocardial fibrosis by regulating the proliferation and activation of CFs triggered by TGF-β1.
STK38 Gene - GeneCards | STK38 Protein | STK38 Antibody
Dec 25, 2024 · STK38 (Serine/Threonine Kinase 38) is a Protein Coding gene. Among its related pathways are RHOBTB GTPase Cycle and Signaling by Rho GTPases. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is STK38L.
TRIM27 cooperates with STK38L to inhibit ULK1 ... - The EMBO …
Jun 7, 2022 · Our study identifies a key role of STK38L‐TRIM27‐ULK1 signaling axis in negatively controlling autophagy with relevance established in human breast cancer. While ULK1 is essential for autophagy initiation, the mechanisms controlling its …
STK38L serine/threonine kinase 38 like - NIH Genetic Testing …
Mar 5, 2024 · Clinical resource with information about STK38L, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.
Stk38 protein kinase preferentially inhibits TLR9-activated ...
May 18, 2015 · Here we demonstrate that Stk38 negatively regulates TLR9-mediated immune responses in macrophages. Stk38 constitutively associates with ubiquitin E3 ligase Smurf1, and facilitates...
Role of STK38L in atrial fibrillation-associated myocardial fibrosis ...
Oct 31, 2024 · To explore the mechanism underlying myocardial fibrosis, we aimed to determine whether serine/threonine kinase 38 like (STK38L) contributes to the development of myocardial fibrosis by regulating the proliferation and activation of CFs triggered by TGF-β1.