Jun 9, 1999 · Objective To determine the frequency and prognosis of the various causes oflow systemic vascular resistance (SVR). Design Analysis of consecutive patients over a 5-year period;retrospective review. Setting Medical intensive care unit of a large university hospital. Patients Fifty-five patients with unexplained hypotension and a SVR lessthan 800 dynes × s/cm5. Background There are minimal data ...

Jun 9, 1999 · CO/body surface area; SVR (dynes×s/cm5)=(80× MAP)/CO; and systemic vascular resistance index (SVRI)=SVR/body surface area. Patients received vaso-pressors to maintain MAP above 70mmHg. The set of hemodynamic data with the lowest SVR was selected for each patient. All historical, clinical, laboratory, microbiologic, and hemo-dynamic data were ...

Nov 19, 2014 · Introduction Functional assessment of arterial load by dynamic arterial elastance (Eadyn), defined as the ratio between pulse pressure variation (PPV) and stroke volume variation (SVV), has recently been shown to predict the arterial pressure response to volume expansion (VE) in hypotensive, preload-dependent patients. However, because both SVV and PPV were obtained from pulse pressure ...

Sep 21, 2010 · Introduction Pulmonary vascular dysfunction, pulmonary hypertension (PH), and resulting right ventricular (RV) failure occur in many critical illnesses and may be associated with a worse prognosis. PH and RV failure may be difficult to manage: principles include maintenance of appropriate RV preload, augmentation of RV function, and reduction of RV afterload by lowering pulmonary vascular ...

Sep 28, 2022 · Hemodynamic monitoring is the centerpiece of patient monitoring in acute care settings. Its effectiveness in terms of improved patient outcomes is difficult to quantify. This review focused on effectiveness of monitoring-linked resuscitation strategies from: (1) process-specific monitoring that allows for non-specific prevention of new onset cardiovascular insufficiency (CVI) in perioperative ...

Feb 4, 2020 · Vasoplegic syndrome is a common occurrence following cardiothoracic surgery and is characterized as a high-output shock state with poor systemic vascular resistance. The pathophysiology is complex and includes dysregulation of vasodilatory and vasoconstrictive properties of smooth vascular muscle cells. Specific bypass machine and patient factors play key roles in occurrence. Research into ...

May 19, 2017 · Background Sodium lactate has been shown to improve hemodynamics and avoid fluid overload. The objective of this study was to confirm a beneficial effect on fluid balance with sodium lactate infusion and to specify whether the advantage of lactate is related to a negative chloride balance, its particular metabolism, or simply its energy load. Methods This was an interventional, randomized ...

Sep 12, 2002 · At 24 hours, a heart rate <95 beats/min, a SVR index >1529 dynes s cm 5 /m 2, a decrease in heart rate >18 beats/min and a decrease in CI >0.5 l/min/m 2 all predicted survival. In a subsequent study [ 14 ], the same authors confirmed previous findings of decreased LVEF and increased LVEDVI in survivors of septic shock but not in non-survivors.

Jan 22, 2024 · Background Following resuscitated out-of-hospital cardiac arrest (OHCA), inflammatory markers are significantly elevated and associated with hemodynamic instability and organ dysfunction. Vasopressor support is recommended to maintain a mean arterial pressure (MAP) above 65 mmHg. Glucocorticoids have anti-inflammatory effects and may lower the need for vasopressors. This study aimed to assess ...

Jul 21, 2023 · Background Vasopressin is a second-line vasoactive agent for refractory septic shock. Vasopressin loading is not generally performed because of the lack of evidence for its effects and safety. However, based on our previous findings, we hypothesized it can predict the responsibility to vasopressin infusion with safety, and prospectively examined it in the present study. Methods Vasopressin ...