Jun 9, 1999 · Objective To determine the frequency and prognosis of the various causes oflow systemic vascular resistance (SVR). Design Analysis of consecutive patients over a 5-year period;retrospective review. Setting Medical intensive care unit of a large university hospital. Patients Fifty-five patients with unexplained hypotension and a SVR lessthan 800 dynes × s/cm5. Background There are minimal data ...

Mar 9, 2010 · The conclusions of this observational study were as follows: 1) Twenty of the 53 patients (37.7%) received a blood transfusion against SRLF recommendations; 2) thirteen of these 20 patients (65%) had an ScvO 2 < 70% and nevertheless seemed to benefit from the blood transfusion (according to the VO 2 /DO 2 relationship), and one may speculate that the fact that they did not comply with the SRLF ...

Jan 17, 2025 · Background Low-volume hypertonic solutions, such as half-molar lactate (LAC), may be a potential treatment used for fluid resuscitation. This study aimed to evaluate the underlying cardiovascular effects and mechanisms of LAC infusion compared to sodium-matched hypertonic sodium chloride (SAL). Methods Eight healthy male participants were randomized in a controlled, single-blinded, crossover ...

Aug 14, 2014 · Introduction Based on the potential interest in sodium lactate as an energy substrate and resuscitative fluid, we investigated the effects of hypertonic sodium lactate in a porcine endotoxic shock. Methods Fifteen anesthetized, mechanically ventilated pigs were challenged with intravenous infusion of E. coli endotoxin. Three groups of five animals were randomly assigned to receive 5 mL/kg/h of ...

Nov 21, 2019 · Background Continuous, reliable evaluation of left ventricular (LV) contractile function in patients with advanced heart failure requiring intensive care remains challenging. Continual monitoring of dP/dtmax from the arterial line has recently become available in hemodynamic monitoring. However, the relationship between arterial dP/dtmax and LV dP/dtmax remains unclear. This study aimed to ...

Oct 11, 2018 · Measurement of arterial pressure is one of the most basic elements of patient management. Arterial pressure is determined by the volume ejected by the heart into the arteries, the elastance of the walls of the arteries, and the rate at which the blood flows out of the arteries. This review will discuss the three forces that determine the pressure in …

Jan 6, 2025 · Background Targeted temperature management (TTM) is considered a beneficial treatment for improving outcomes in patients with OHCA due to acute coronary syndrome (ACS). The comparative benefits of hypothermic TTM (32–34°C) versus normothermic TTM (35–36°C) are unclear. This study compares these TTM strategies in improving neurological outcomes and survival rates in OHCA patients with ACS ...

Jan 24, 2014 · The residual variability was ascribed to a proportional model. BSVs were estimated for HR 0, C 50 HR, SV.SVR 0 and SV.SVR max. Age was the main covariate influencing HR 0 and SV ⋅ SVR 0 (P <0.001) where HR 0i = HR 0 × age i-0.0612 and SV.SVR 0i = SV ⋅ SVR 0 × age i 0.094 respectively. Including age in the model dramatically decreased the ...

Nov 8, 2023 · Background Pulse pressure and stroke volume variation (PPV and SVV) have been widely used in surgical patients as predictors of fluid challenge (FC) response. Several factors may affect the reliability of these indices in predicting fluid responsiveness, such as the position of the patient, the use of laparoscopy and the opening of the abdomen or the chest, combined FC characteristics, the ...

Dec 3, 2010 · Several prognostic markers have been identified for patients admitted with acute cardiogenic pulmonary edema. Most of the markers are based on clinical risk scores. Unlike hypercapnic respiratory failure, acidosis is not an adverse predictor in these patients. Hemodynamic variables that assess pathophysiological mechanisms may be more helpful to guide appropriate management.