Polyclonal Antibody for studying STAT3. Validated for ChIP, IHC, IP, WB. Highly specific and rigorously validated in-house, Stat3 Antibody (CST #9132) is ready to ship.

Phospho-Stat3 (Tyr705) (D3A7) XP ® Rabbit mAb detects endogenous levels of Stat3 only when phosphorylated at tyrosine 705. This antibody does not cross-react with phospho-EGFR or the corresponding phospho-tyrosines of other Stat proteins.

Dec 25, 2024 · STAT3 (Signal Transducer And Activator Of Transcription 3) is a Protein Coding gene. Diseases associated with STAT3 include Hyper-Ige Syndrome 1, Autosomal Dominant, With Recurrent Infections and Autoimmune Disease, Multisystem, Infantile-Onset, 1 .

Stat3 (124H6) Mouse mAb detects endogenous levels of total Stat3 protein. Human, Mouse, Rat, Monkey. Monoclonal antibody is produced by immunizing animals with a synthetic peptide centered around amino acid Gln692 of human Stat3.

STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT3 is phosphorylated by receptor-associated Janus kinases (JAK), forms homo- or heterodimers, and translocates to the cell nucleus where it acts as a transcription activator.

To determine whether mitochondrial STAT3 exists in multimeric complexes, proteins were eluted from capture beads and separated by size-exclusion chromatography, which revealed that mitochondrial STAT3 predominantly exists in a ∼400 kDa complex with minor species at ∼670 and ∼100 kDa; this latter peak is consistent with the known size of ...

50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. Store at -80°C. Aliquot to avoid repeated freezing and thawing. Best use within three months from the date of receipt of this protein. The protein encoded by this gene is a member of the STAT protein family.