C6 is a glial cell line that was isolated from the brain of a rat with Glioma. The glial tumor was induced by N-nitrosomethylurea after a series of alternate culture and animal passages. This …

The C6 rat glioma model is one of the commonest experimental models used in neuro-oncology in order to study the growth and the invasion of high-grade gliomas. A recent MRI and magnetic …

Rodent brain tumor models have been useful for developing effective therapies for glioblastomas (GBMs). In this review, we first discuss the 3 most commonly used rat brain tumor models, the …

In this review we will describe eight commonly used rat brain tumor models and their application for the development of novel therapeutic and diagnostic modalities. The C6, 9L and T9 …

Dec 14, 2017 · In the present study, we analyzed immune heterogeneity in rat C6 gliomas and kinetics of immune cell infiltration of GAMs, MDSCs and T cell subpopulations. We found …

The C6 glioma cell line was cloned from an intravenous MNU-induced glioma tumor in a random-bred Wistar rat (65). The line is well characterized, stable, and readily available; it grows very …

Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas. The complete mitochondrial genome sequence of the rat C6 glioma cell …

Tumors derived from rat C6 cell implants into rat brain exhibit similar morphological characteristics and degree of vascularization to human glioblastomas. To establish a molecular basis for C6 …

The cell line C6 was established from rat glial tumor induced by N-nitrosomethylurea. (Benda et al., 1968) Recommended propagation method. Culture medium: 82.5% Ham’s F12 + 15% …

The C6/lacZ cell line was developed in 1989 from the C6 cell line (N-nitrosomethylurea induced rat glial tumor). The cells constitutively express the lacZ reporter gene product, E. coli derived …