Nov 8, 2021 · A fusion protein comprising an antibody and a cationic peptide, such as arginine-9 (R9), is a candidate molecule for efficient and cell-specific delivery of siRNA into cells in order …

Sep 9, 2016 · Moreover, in order to evaluate the utility of the peptides as intracellular delivery tools, we examined the stability, cytotoxicity, and endosomal escape functions of peptides 1–5 …

Apr 5, 2024 · Cell Penetrating Peptides (CPPs) are short peptides that can transport molecular cargo into cells. What is R9? R9 is a type of CPP consisting of nine arginine residues, and it is …

A fusion protein comprising an antibody and a cationic peptide, such as arginine-9 (R9), is a candidate molecule for efficient and cell-specific delivery of siRNA into cells in order to reduce …

Apr 15, 2020 · In the slightly acidic tumor extracellular environment (∼pH 6.5), tumor acidity-activatable polyanionic polyphosphoester would be deshielded from the nanoparticles, …

Nov 5, 2024 · The MR peptide is a fusion of R9 with two membrane-active peptides, namely cecropin and melittin. This fusion peptide possesses cell-penetrating properties. Huh7 cells …

Nona-arginine (R9), dodeca-arginine (R12) as well as Flock-House-Virus-derived peptide, also lead to cell internalization via macropinocytosis [65–67]. Furthermore, it is possible that …

Jun 7, 2018 · Herein, we report that an r9 cell-penetrating peptide-based cabazitaxel nanovehicle (r9-CN) displays prominent lymph metastasis targeting and deep penetration ability after …

Jan 6, 2022 · Cell-penetrating peptides (CPPs) are a class of short peptides, which have the ability of intracellular delivery. CPPs can also be used as an ideal transfection tool whereby …

Aug 1, 2015 · By physicochemically evaluating peptide/pDNA complexes and performing in vitro assays of peptides and peptide/pDNA complexes against cultured cells, R9 peptides were …