PDBe-KB provides an overview of all the structure information available in the PDB for Human cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A)

Dec 25, 2024 · PRKAR1A (Protein Kinase CAMP-Dependent Type I Regulatory Subunit Alpha) is a Protein Coding gene. Diseases associated with PRKAR1A include Myxoma, Intracardiac …

The PRKAR1A gene provides instructions for making one part (subunit) of an enzyme called protein kinase A. This enzyme promotes cell growth and division (proliferation). Protein kinase …

Carney complex is a genetic disorder. The condition happens when there is a mutation in the PRKAR1A gene. DNA in this gene tells your body how to make an enzyme that controls how a …

Dec 20, 2016 · Protein Kinase cAMP-Dependent Regulatory Type I Alpha (PRKAR1A) is a tissue-specific extinguisher that transduces a signal through phosphorylation of different...

PRKAR1A is a potent tumor suppressor that inhibits the ERK/Snail/E-cadherin pathway in lung adenocarcinoma; t-Darpp phosphorylation at T39 seems to be crucial for t-Darpp-mediated …

In 2000, we identified inactivating germline mutations of the PRKAR1A gene, encoding the regulatory subunit type 1α (RIα) of protein kinase A (PKA), in the majority of patients with CNC …

Dec 1, 2004 · The type 1α regulatory subunit (RIα) of cAMP-dependent protein kinase (PKA) (coded by the PRKAR1A gene) is the main component of type I PKA, which regulates most of …

PRKAR1A is a critical component of type I protein kinase A (PKA), the main mediator of cAMP signaling in mammals. PKA is a tetramer consisting of 2 regulatory and 2 catalytic subunits. It …

The type 1alpha regulatory subunit (RIalpha) of cAMP-dependent protein kinase (PKA) (coded by the PRKAR1A gene) is the main component of type I PKA, which regulates most of the serine …