Protein kinase C-associated kinase regulates NF-κB activation ... - PubMed
Unlike other members of the RIP family that activate NF-κB through a kinase-independent pathway, PKK appears to activate IKK and NF-κB mainly in a kinase-dependent manner. …
NF-κB activation by protein kinase C isoforms and B-cell function
The recent generation of additional KO mice for adapters and kinases implicated in NF-κB activation, including several protein kinase C isoforms, has provided new insights into the roles …
The PKC/NF-κB signaling pathway induces APOBEC3B expression …
Nov 1, 2015 · Activation of protein kinase C (PKC) by the diacylglycerol mimic phorbol-myristic acid resulted in specific and dose-responsive increases in APOBEC3B expression and activity, …
The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression …
Nov 1, 2015 · Here, we show that the protein kinase C (PKC)/NF-κB pathway specifically induces APOBEC3B expression, providing the first mechanistic link between a major signal …
PKC ζ at the crossroad of NF-κB and Jak1/Stat6 signaling pathways
Dec 2, 2005 · The atypical protein kinase C (PKC) isoforms (aPKC) have been implicated in the regulation of a number of essential signaling events.
Phorbol ester-stimulated NF-kappaB-dependent transcription: …
Since protein kinase C (PKC) isoforms are variously implicated in the activation of NF-kappaB, we have investigated the role of PKC in the activation of NF-kappaB-dependent transcription by …
From Calcium to NF-κB Signaling Pathways in Neurons - PMC
In addition, the Ca 2+ signal may also synergize with other signaling pathways, as is the case for protein kinase C (PKC) activation in T lymphocytes (26, 82, 86). However, the exact process …
NF-κB signaling pathways regulated by CARMA family of ... - Nature
Dec 28, 2010 · The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially …
The complexity of NF-κB signaling in inflammation and cancer
The NF-κB family of transcription factors has an essential role in inflammation and innate immunity. Furthermore, NF-κB is increasingly recognized as a crucial player in many steps of …
calcium/nuclearfactorofactivatedTcells(NFAT)andproteinkinaseC(PKC)/nuclearfactorkB(NF-kB),inte-grate through a dynamic and combinatorial strategy to fine-tune T cell response …