
PDK1 Gene - GeneCards | PDK1 Protein | PDK1 Antibody
Dec 25, 2024 · PDK1 (Pyruvate Dehydrogenase Kinase 1) is a Protein Coding gene. Diseases associated with PDK1 include Pyruvate Dehydrogenase E3-Binding Protein Deficiency and …
Pyruvate dehydrogenase kinase - Wikipedia
Pyruvate dehydrogenase kinase (also pyruvate dehydrogenase complex kinase, PDC kinase, or PDK; EC 2.7.11.2) is a kinase enzyme which acts to inactivate the enzyme pyruvate …
Pyruvate dehydrogenase kinases (PDKs): an overview toward …
This review seeks to elucidate the regulation of PDK activity in different species, mainly mammals, and the role of PDK inhibitors in preventing increased blood glucose, reducing injury caused …
Pan-cancer analysis reveals PDK family as potential indicators …
Mar 7, 2024 · Our study uncovers pronounced genetic heterogeneity among PDK family members, coupled with discernible clinical characteristic. Significantly, the study establishes …
PDK1 pyruvate dehydrogenase kinase 1 [Homo sapiens (human)] - Gene …
Jan 4, 2025 · Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. …
Pyruvate Dehydrogenase Kinases: Therapeutic Targets for …
PDC activity is tightly regulated using phosphorylation by pyruvate dehydrogenase kinases (PDK1 to 4) and pyruvate dehydrogenase phosphatases (PDP1 and 2). PDKs and PDPs exhibit …
Three members of the human pyruvate dehydrogenase kinase gene …
Sep 14, 2007 · Here, we show that they are direct regulators of the family of pyruvate dehydrogenase kinase (PDK) genes, whose products act as metabolic homeostats in sensing …
Pyruvate dehydrogenase kinases (PDKs): an overview toward ... - PubMed
Apr 30, 2021 · Pyruvate dehydrogenase kinase (PDK) can regulate the catalytic activity of pyruvate decarboxylation oxidation via the mitochondrial pyruvate dehydrogenase complex, …
Transcriptional Regulation of Pyruvate Dehydrogenase Kinase
In this review, we discuss several factors involved in the expressional regulation of PDK2 and PDK4, and introduce current studies aimed at providing a better understanding of the …
The expression pattern of pyruvate dehydrogenase kinases …
May 5, 2023 · The pyruvate dehydrogenase kinases (PDK; four genes: PDK1-4) are major regulatory subunits of the PDH complex, since phosphorylation of E1 catalytic subunit by PDK …