
Preparation and evaluation of a …
In this study, we aimed to fabricate and characterize an electrospun nanofibrous mat containing polycaprolactone (PCL), chitosan (CTS), and propolis for use as a tissue-engineered skin substitute. Methods: Raw propolis was extracted, and …
In vivo analysis of vascularization and biocompatibility of …
May 29, 2019 · In this study, using the femur chamber in rats, we demonstrated that CS‐g‐PCL modification of PCL fibre mats improved angiogenesis in vivo. Currently, tissue regeneration after defects independent of the field of application is limited by the absence of proven strategies for the generation of adequately vascularized tissues (Schumann et al ...
Preparation and evaluation of a …
Jun 11, 2023 · In this study, we aimed to fabricate and characterize an electrospun nanofibrous mat containing polycaprolactone (PCL), chitosan (CTS), and propolis for use as a tissue-engineered skin substitute. Raw propolis was extracted, and its phenolic and flavonoid contents were measured.
Electrospun Polycaprolactone Nanofibers: Current Research and ...
Several types of PCL and delivery systems based on PCL have been defined, including nanoparticles, microparticles, electrospun mats, films, and scaffolds that we focused on electrospun PCL/nanofiber applications in drug delivery.
Fabrication of tri-layered electrospun polycaprolactone mats with ...
Oct 23, 2020 · Modulation of initial burst and long term release from electrospun fibrous mats can be achieved by sandwiching the drug loaded mats between hydrophobic layers of fibrous polycaprolactone (PCL).
Vascularization and biocompatibility of poly(ε-caprolactone) fiber mats …
Jan 13, 2020 · In order to promote vascularization of implant material, we compared a porous polymer patch (a commercially available porous polyurethane based scaffold from Biomerix™) with electrospun polycaprolactone (PCL) fiber mats and chitosan-graft-PCL coated electrospun PCL (CS-g-PCL) fiber mats in vivo.
In vivo analysis of vascularization and biocompatibility of …
Jul 9, 2020 · We compared a porous polymer patch (a commercially available porous polyurethane-based scaffold from Biomerix™) with electrospun polycaprolactone (PCL) fibre mats and chitosan (CS)-graft-PCL modified electrospun PCL (CS-g-PCL) fibre mats in vivo.
In vitro and in vivo evaluations of phenytoin sodium-loaded
Dec 19, 2012 · The release rate measurements by HPLC showed that the PVA nanofibrous sample containing phenytoin sodium (PHT-Na) has a higher level of the drug release compared to the hybrid PVA/PCL (80/20) and PCL nanofibrous mats.
Combination of mesenchymal stem cell sheet with poly ... - PubMed
Apr 28, 2024 · This study aimed to investigate the osteogenic properties of adipose-derived-mesenchymal stem cell (AD-MSC) sheets combined with nanofibrous poly-caprolactone (PCL) mat and Gelfoam in rats with calvarial bone defect.
PCL (CS‐g‐PCL) fibre mats in vivo. By means of intravital fluorescence microscopy, microhaemodynamic parameters were analysed repetitively over 20 days at intervals