In this study, we aimed to fabricate and characterize an electrospun nanofibrous mat containing polycaprolactone (PCL), chitosan (CTS), and propolis for use as a tissue-engineered skin substitute. Methods: Raw propolis was extracted, and …

May 29, 2019 · In this study, using the femur chamber in rats, we demonstrated that CS‐g‐PCL modification of PCL fibre mats improved angiogenesis in vivo. Currently, tissue regeneration after defects independent of the field of application is limited by the absence of proven strategies for the generation of adequately vascularized tissues (Schumann et al ...

Jun 11, 2023 · In this study, we aimed to fabricate and characterize an electrospun nanofibrous mat containing polycaprolactone (PCL), chitosan (CTS), and propolis for use as a tissue-engineered skin substitute. Raw propolis was extracted, and its phenolic and flavonoid contents were measured.

Several types of PCL and delivery systems based on PCL have been defined, including nanoparticles, microparticles, electrospun mats, films, and scaffolds that we focused on electrospun PCL/nanofiber applications in drug delivery.

Oct 23, 2020 · Modulation of initial burst and long term release from electrospun fibrous mats can be achieved by sandwiching the drug loaded mats between hydrophobic layers of fibrous polycaprolactone (PCL).

Jan 13, 2020 · In order to promote vascularization of implant material, we compared a porous polymer patch (a commercially available porous polyurethane based scaffold from Biomerix™) with electrospun polycaprolactone (PCL) fiber mats and chitosan-graft-PCL coated electrospun PCL (CS-g-PCL) fiber mats in vivo.

Jul 9, 2020 · We compared a porous polymer patch (a commercially available porous polyurethane-based scaffold from Biomerix™) with electrospun polycaprolactone (PCL) fibre mats and chitosan (CS)-graft-PCL modified electrospun PCL (CS-g-PCL) fibre mats in vivo.

Dec 19, 2012 · The release rate measurements by HPLC showed that the PVA nanofibrous sample containing phenytoin sodium (PHT-Na) has a higher level of the drug release compared to the hybrid PVA/PCL (80/20) and PCL nanofibrous mats.

Apr 28, 2024 · This study aimed to investigate the osteogenic properties of adipose-derived-mesenchymal stem cell (AD-MSC) sheets combined with nanofibrous poly-caprolactone (PCL) mat and Gelfoam in rats with calvarial bone defect.

PCL (CS‐g‐PCL) fibre mats in vivo. By means of intravital fluorescence microscopy, microhaemodynamic parameters were analysed repetitively over 20 days at intervals