Polyclonal Antibody for studying SQSTM1. Validated for WB. Available in 2 sizes. Highly specific and rigorously validated in-house, SQSTM1/p62 Antibody (CST #5114) is ready to ship.

Jun 17, 2024 · SQSTM1 Antibody (D-3) is a mouse monoclonal IgG1 kappa light chain antibody specifically designed to detect human SQSTM1 protein, also known as p62, across applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent ...

p62/SQSTM1 antibody used for IHC-Fr and WB on samples from Trembler J (TrJ) mice, which carry the same leucine to proline substitution in peripheral myelin protein 22 (PMP22; linked to Charcot--Marie-Tooth disease type 1A/CMT1A).

The p62 protein/sequestosome 1 (SQSTM1) is a multifunctional protein, which binds to ubiquitin. It acts as a scaffold protein for the nuclear factor kappa-B (NF-ΚB) signaling pathway. SQSTM1 also regulates apoptosis and autophagy.

Phospho-SQSTM1/p62 (Thr269/Ser272) Antibody recognizes endogenous levels of SQSTM1 protein only when phosphorylated at Thr269 and Ser272. This antibody may react with either dually or singly phosphorylated SQSTM1/p62. A background band is …

Sequestosome 1 (SQSTM1/p62) is a multifunctional adaptor protein implicated in selective autophagy, cell signaling pathways, and tumorigenesis. p62 has been implicated in shuttling ubiquitinated and aggregated proteins for autophagic degradation. p62 is degraded during the autophagic process, which makes its intracellular level a marker for ...

Mar 2, 2025 · This protein directly interacts with LC3, which is localized on autophagosome membrane, and is degradated by autophagic-lysosome pathway. p62 regulates ubiquitin-positive protein aggregates caused by autophagy deficiency. Waguri S, Komatsu M. Biochemical and morphological detection of inclusion bodies in autophagy-deficient mice.