Patients with acute tubulointerstitial nephritis with uveitis are diagnosed by clinical recognition of concurrent uveitis. Necrotizing glomerulonephritis or vasculitis is commonly associated with active interstitial inflammation that, in limited samples with no glomeruli, may be mistaken as AIN.

May 19, 2024 · Identify the clinical signs and symptoms associated with tubulointerstitial nephritis (TIN) to facilitate early diagnosis. Conduct thorough diagnostic assessments, including laboratory tests, renal imaging, and histological examination, to confirm the diagnosis accurately.

Jan 29, 2024 · Global glomerulosclerosis is characterized by shrunken and retracted glomerular tuft with PAS positive glomerular basement membrane remaining and faintly PAS positive fibrous matrix replacing Bowman space.

Chronic interstitial nephritis is a nonspecific diagnosis of a pattern of kidney injury, which may occur due to any of many conditions that initially cause an acute interstitial nephritis. The diagnosis is made when specific underlying causes cannot be identified.

The AJKD Atlas of Renal Pathology II updates the original Atlas by providing, in each installment, key, systematically presented information on a specific pathologic entity, as well as representative images.

Lupus nephritis is a renal manifestation of systemic lupus erythematosus (SLE) that displays a broad spectrum of histologic changes.

The spectrum of morphologic changes in lupus nephritis, either microscopic, ultrastructural, or immunohistological, closely reflects the great variety of immune complexes that are produced in the course of the disease.

Jun 21, 2019 · The main histologic finding in AIN is a mixed interstitial inflammatory infiltrate, often associated with tubulitis and interstitial edema. The appearances are often similar despite varied mechanisms, but there are certain pathologic clues which may suggest a particular etiology, detailed below. Figure 1. Acute interstitial nephritis, H&E stain.

Jun 26, 2023 · Etiological classification of glomerulonephritis can be made based on clinical presentation, ranging from severe proteinuria (>3.5 g/day) and edema qualifying for the nephrotic syndrome to a nephritic syndrome where hematuria and hypertension are more prominent while proteinuria is less pronounced. Nephrotic Glomerulonephritis.

Feb 17, 2023 · Renal histology is highly specialized in different nephron segments, providing crucial information for diagnosing several kidney diseases. [2] Macroscopically, the kidney divides into two sections: the renal cortex, the outer part of the kidney, and the medulla, the inner section.