Jul 29, 2021 · Here, we introduce an easy-to-use model system of the myelin sheath that can be used to study myelin proteins in a native-like yet well-controlled environment. To this end, we …

In the proposed treadmilling model, myelin sheath thickness is a dynamic balance between the rates of new myelin deposited adjacent to the axon and removal of the outermost layer. The …

May 10, 2021 · This 'myelionoid' stem cell model can mimic key processes in the development of the myelin sheath, essential for myelination treatments.

This set of experiments showcases that myelinoids are a model in which myelin sheath characteristics are tunable and quantifiable—two essential features if this model is to be used …

In the proposed treadmilling model, myelin sheath thickness is a dynamic balance between the rates of new myelin deposited adjacent to the axon and removal of the outermost layer. …

we introduce an easy-to-use model system of the myelin sheath that can be used to study myelin proteins in a native -like yet well-controlled environment. To this end, we present myelin …

Here, we for the first time establish nanodiscs with the challenging lipid composition of myelin of the peripheral or central nervous systems, respectively (PNS and CNS, both containing >40% …

Myelin is the lipidic insulating structure enwrapping axons and allowing fast saltatory nerve conduction. In the central nervous system, myelin sheath is the result of the complex …

Sep 13, 2021 · Here, we introduce an easy-to-use model system of the myelin sheath that can be used to study myelin proteins in a native-like yet well-controlled environment. To this end, we …

Jun 23, 2021 · To achieve this we used molecular models to describe sub-cellular components of the myelinated axon, in particular myelin sheath and node of Ranvier, and a FE simulations of …