9 of 12 lupin seed-allergic individuals have IgE that recognized Lup an 1. Click on the arrows to show the details of individual isoallergens, click on +/- to show/hide the details of all isoallergens.

Lup-20(29)-en-3-one | C30H48O | CID 323075 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

The major lupin allergen Lup an1 (β-conglutin) has sequence similarities to the major peanut allergen Ara h1. Generally, lupin allergens are resistant to thermal, chemical, and proteolytic degradation.

Oct 13, 2021 · In this study, we have immunized an alpaca with lupine protein extracts and retrieved nanobodies (Nbs). Nevertheless, the target antigen has been recognized as Lup an 1, which has been classified as β-conglutin, and confirmed to connect with lupine allergy.

Oct 13, 2021 · In this study, we have immunized an alpaca with lupine protein extracts and retrieved nanobodies (Nbs). Nevertheless, the target antigen has been recognized as Lup an 1, which has been classified as ?-conglutin, and confirmed to connect with lupine allergy.

Oct 18, 2019 · The current study developed a new highly specific, sensitive and accurate ELISA method to detect, identify and quantify the lupin main allergen β-conglutin (Lup an 1) protein in natural and processed food.

Using in vitro selection, high affinity DNA aptamers to the food allergen Lup an 1, ß-conglutin, were selected from a pool of DNA, 93 bases in length, containing a randomised sequence of 49 bases. ß-conglutin was purified from lupin flour and chemically crosslinked to carboxylated magnetic beads.

The major lupin allergen Lup an1 (β-conglutin) has sequence similarities to the major peanut allergen Ara h1. Generally, lupin allergens are resistant to thermal, chemical, and proteolytic degradation.

In this paper we report the truncation of an aptamer that specifically binds to β-conglutin (Lup an 1), an anaphylactic allergen. Through comparing the predicted secondary structures of the aptamers, a hairpin structure with a G-rich loop was determined to be the binding motif.

May 4, 2012 · Major allergen Lup an1 characterized from lupine which belongs to seed storage protein family (vicilin like protein). Recently, two more allergens have been identified in lupine namely Lup a vicilin and Lup an 11S globulin, both belong to cupin superfamily.