Ki-67 was first identified as an antigen in Hodgkin lymphoma cell nuclei (Gerdes et al. 1983) that is highly expressed in cycling cells but strongly down-regulated in resting G0 cells (Gerdes et …

Method: In the present work, we have compared Ki-67 expression (detected with MIB1 antibody) with PCNA expression (detected with PC10 antibody) in biopsies of normal human epidermis …

In this structure, Ki-67 acts to prevent aggregation of mitotic chromosomes. Here, we present an overview of functional roles of Ki-67 across the cell cycle and also describe recent …

A high Ki67 proliferation rate (n = 18) favored a diagnosis of melanoma or nevi requiring re-excision (15/18, 83.3%) versus a benign nevus (3/18, 16.67%). A high Ki67 rate was 71.4% …

Ki67 is a non-histonic protein which is mainly interfere with the proliferation and has many controlling effects during the cell cycle. Because of their importance in skin tumor cell growth, …

Feb 7, 2025 · Increased Ki67 levels are associated with hair growth, allowing researchers to differentiate between types of alopecia, such as AGA and telogen effluvium, where elevated …

Jul 31, 2015 · Because psoriasis is a hyperproliferative skin disorder with increased epidermal turnover rate and mitotic index, we investigated the role of proliferation markers Ki-67 and …

Immunohistochemical staining patterns for CK17 and Ki-67 were evaluated in 24 KA and 27 SCC cases. The pattern of staining was evaluated as central, peripheral or diffuse, according to the …

These results indicate that pumpless SOC can be used as an in vitro skin model similar to human skin, protein and gene expression can be analyzed, and it can be used for functional drug tests...

The Ki-67 protein is expressed in the nucleus and is a marker for cell proliferation. Increased number of Ki-67 positive cells in epidermis indicates increased epidermal hyperplasia, a …