Measurement of T regs, Ki-67+CD4+ and Ki-67+CD8+ T cells may help to early distinguish patients that will benefit from pharmacological intervention. We now continue to collect patient data, also including patients under treatment with immunosuppressant and resolving patients.

We investigated CD4 + and CD8 + T cell turnover in both healthy and HIV-1–infected adults by measuring the nuclear antigen Ki-67 specific for cell proliferation.

Apr 20, 1998 · We investigated CD4+ and CD8+ T cell turnover in both healthy and HIV-1-infected adults by measuring the nuclear antigen Ki-67 specific for cell proliferation.

Apr 8, 2021 · The possibility that Ki-67 expression could reflect a recent post-mitotic state was reinforced by BrdU pulse-chase data, showing that BrdU-labeled CD4 T EM and T CM cells were still Ki-67 + 4 days after BrdU-treatment withdrawal .

Jun 29, 2012 · Measurement of Ki-67 reveals CD4 T cell responses to influenza vaccination. Influenza specific CD4 T cells respond transiently to vaccination. Influenza vaccination may reshape the T cell memory response. Ki-67 provides a …

Oct 29, 2019 · Multivariate analyses of pathological and immunological features and prognosis revealed that carcinoma Ki67 high CD4 + T cells after CRT and stromal Ki67 high CD8 + T cells after NAC are important prognostic factors, respectively.

Jun 29, 2012 · At 4-6 days after vaccination, there is a sharp rise in the numbers of Ki-67-expressing PBMC that produce IFNγ, IL-2 and/or TNFα in vitro in response to influenza vaccine or peptide.

CD4 T cells in the mucosa were found to harbor two major population of cells; ~25% of CD4 T cells expressed the α4 + β7 hi phenotype, whereas the rest of the 75% expressed an α4 + β7 int phenotype. Both the subsets were predominantly CD28 + Ki-67 − HLA-DR − but CD69 +, and expressed detectable levels

Jul 22, 2022 · Within antigen-responsive CD4 + T-cells, CD27-and CD38 + (ESAT-6/CFP-10-specific), and HLA-DR + and Ki-67 + (PPD- and ESAT-6/CFP-10-specific) populations were significantly increased in aTB compared to LTBI. Ki-67 demonstrated the best discriminative performance as evaluated by ROC analyses (AUC > 0.9 after PPD stimulation).

3 days ago · CD4 + Foxp3 − T cells from the ... In addition, we found that Ki-67 + T regs were decreased in Atf4-deficient resting T regs and that Bcl-2 interacting mediator of cell death (Bim) + T regs were increased in Atf4-deficient effector T regs (fig. S8, E and F). ATF4 functions as both a transcriptional activator and transcriptional repressor .