Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the IL15RA gene. [5] The IL-15 receptor is composed of three subunits: IL-15R …

Dec 25, 2024 · IL15RA (Interleukin 15 Receptor Subunit Alpha) is a Protein Coding gene. Diseases associated with IL15RA include Capillary Disease and Capillary Leak Syndrome. …

Gene ID: 3601, updated on 8-Feb-2025. This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, …

Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. [2] The IL-15 receptor is composed of the IL-2Rβ and γc subunits, along with a unique ligand-specific subunit, IL …

Recently, the creation of IL-15 superagonist by complexing IL-15 and its high affinity receptor alpha (IL-15 Rα) in solution, inspired by the natural trans-presentation of IL-15, advances the …

Feb 8, 2025 · Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported …

Know comprehensive IL-15 R alpha/IL15RA protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction.

Jul 22, 2007 · Here we present a 1.85-Å crystal structure of the human IL-15–IL-15Rα complex. The structure provides insight into the molecular basis of the specificity of cytokine recognition …

Dec 1, 2008 · IL-15 is critical for natural killer (NK)–cell development and function and for memory CD8 + T-cell homeostasis. The IL-15 receptor consists of IL-15Rα, IL-2Rβ, and the common …

Feb 8, 2025 · IL-15 is a particularly important regulator of natural killer development, differentiation, homeostasis, and activation. data reveal a critical function of Shp-2 as a …