Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, …

The cytokine, granulocyte macrophage-colony stimulating factor (GM-CSF), was firstly identified as being able to induce in vitro the proliferation and differentiation of bone marrow progenitors …

Jul 5, 2022 · Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that drives the generation of myeloid cell subsets including neutrophils, monocytes, macrophages, …

Granulocyte macrophage colony-stimulating factor (GM-CSF) is a cytokine that promotes myeloid cell development and maturation, and dendritic cell differentiation and survival in vitro. …

The role of granulocyte-macrophage-colony-stimulating factor (GM-CSF) in the supportive care of cancer patients has been evaluated with promising results. More recently, GM-CSF has been …

GM-CSF, or granulocyte-macrophage colony-stimulating factor, is a powerful medication that can help boost your immune system, particularly in cancer treatment or bone marrow recovery. …

Jul 19, 2021 · Granulocyte-macrophage colony-stimulating factor (GM-CSF), which belongs to the colony-stimulating factor (CSF) superfamily and was originally identified as a hemopoietic …

GM-CSF was originally identified as a colony stimulating factor (CSF) because of its ability to induce granulocyte and macrophage populations from precursor cells. Multiple studies have …

Feb 13, 2006 · Granulocyte-macrophage colony-stimulating factor (GM-CSF) is an important hematopoietic growth factor and immune modulator. GM-CSF also has profound effects on the …

Dec 3, 2015 · Granulocyte-macrophage colony stimulating factor (GM-CSF) is a growth factor first identified as an inducer of differentiation and proliferation of granulocytes and macrophages …

Jan 6, 2020 · Granulocyte-macrophage colony-stimulating factor (GM-CSF) has many more functions than its original in vitro identification as an inducer of granulocyte and macrophage …

The granulocyte-macrophage colony-stimulating factor (GM-CSF) produced by activated γδ T cells is a potent species-specific stimulator of precursors of granulocytes, macrophages and …

Granulocyte-colony stimulating factor (G-CSF) is a glycoprotein, the second CSF, sharing some common effects with granulocyte macrophage-colony stimulating factor (GM-CSF), interleukin …

Nov 15, 2016 · GM-CSF has initially been categorized as a hematopoietic growth factor involved in steady-state myelopoiesis. However, it now emerges as a critical communication conduit …

GM-CSF binds to the multimeric GM-CSFR, comprising a specific low-affinity ligand-binding α subunit (GM-CSFRα) and a signal-transducing β subunit (GM-CSFRβ), the latter shared with …

GM-CSF differentiates bone marrow precursosrs into tolerogenic dendritic cells that can 1) induce adaptive Tregs through secretion of TGF-β and 2) cause proliferation of natural Tregs through …

GM-CSF is produced by a variety of cell types (monocytes, endothelial cells, T-cells, fibroblasts, mitogen-stimulated B-cells, and LPS-stimulated macrophages). GM-CSF is secreted as a …

GM-CSF assembles and activates its heterodimeric receptor complex on the surface of myeloid cells, initiating multiple signaling pathways that control key functions such as cell survival, cell …

Background: Injection site reactions (ISR) of booster injections in the randomized, active-controlled, single-blinded, multicenter Phase IIb trial of GLSI-100 (GP2+GM-CSF) …

Autoantibodies to multiple cytokines have been identified and some, including antibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF), have been associated with …