Thermo Scientific DTT (DL-Dithiothreitol; Clelands reagent) is used to stabilize enzymes and other proteins, which possess free sulfhydryl groups. It has been shown to restore activity lost by oxidation of these groups in vitro.

Order DL-Dithiothreitol (DTT) powder, a reducing agent commonly used in protein sample buffers to break protein disulfide bonds prior to SDS-PAGE. Available at Sigma-Aldrich.

Thermo Scientific Pierce DTT (Dithiothreitol), No-Weigh format, is offered as 7.7 mg x 48-tube microplates for convenient preparation of 100 μL of 0.5 M single-use stocks for addition to protein samples for effective reduction of disulfide bonds.

DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl)cystamine to break apart the matrix of a polyacrylamide gel. DTT is less pungent and is less toxic than 2-mercaptoethanol.

Dithiothreitol (DTT) is an organosulfur compound with the formula (CH (OH)CH2SH)2. A colorless compound, it is classified as a dithiol and a diol. DTT is redox reagent also known as Cleland's reagent, after W. Wallace Cleland. [2] . The reagent is commonly used in its racemic form. Its name derives from the four-carbon sugar, threose.

Dithiothreitol is a popular reducing agent for many protein research applications, including reducing polyacrylamide electrophoresis (SDS-PAGE). For Research Use Only. Not for use in diagnostic procedures.

DL-dithiothreitol (DTT) is used in a chemical debonding technique, that helps to remove bacteria from biofilms. It can change the structural stability of the GABA(B) (gamma-aminobutyric acid) receptor by disabling the disulfide bonds between four cysteine residues positioned in the GABA(B1(a)) receptor structure. Dithiothreitol (DTT) is broadly utilized in synthetic peptide synthesis and ...

DTT is a nearly 7-fold stronger reduction agent than βME (β-mercaptoethanol) and does not have the repulsive smell or toxicity of βME. GoldBio’s DTT is the purest DTT on the market and is Proven and Published™ to ensure a quality reagent with optimal potential. Showing 1-1 of 1 item.

Dithiothreitol (DTT), one of Cleland’s reagents, is a popular reducing agent that reduces disulfide bridges, breaking polyacrylamide gel matrices.

1. What is DTT? DTT is a protective agent for reducing S-S TO SH groups. Used as a strong reducing agent for proteins and enzymes. Enhances DNA polymerase activity. 2. Are there alternative names? Dithiothreitol; Cleland's reagent (discovered by W.W. Cleland, University of Wisconsin) CAS 3483-12-3; 3. What is the chemical formula? C 4 H 10 O 2 ...