Feb 24, 2025 · Cervical intraepithelial neoplasia (CIN) is a premalignant squamous lesion of the uterine cervix diagnosed by cervical biopsy and histologic examination . The goal of management is to prevent possible progression to cancer while avoiding overtreatment since lesions can spontaneously regress and treatment can have morbid effects.

Feb 24, 2025 · Accurate pretreatment staging of cervical cancer is critical, as it determines therapy (ie, surgery, chemoradiation, chemotherapy alone) and prognosis . The staging and evaluation of lymph nodes for cervical cancer will be reviewed here.

Apr 10, 2024 · Patients with low-grade CIN have minimal potential for developing cervical malignancy, while those with high-grade lesions are at high risk of progression to malignancy. The definition, incidence, and pathogenesis of CIN are reviewed here.

High-grade squamous lesions (cervical intraepithelial neoplasia [CIN] 2 or 3) have a high risk of persisting or developing into cervical cancer over a period of years. If you are age 25 and older and not pregnant, CIN 2 or 3 is treated by removing or destroying the abnormal area.

The relative rarity of VaIN, which is far less common than vulvar intraepithelial neoplasia (VIN) or cervical intraepithelial neoplasia (CIN), is an impediment to a thorough understanding of the disease process and its natural course.

Patients with HIV infection have higher rates of preinvasive (ie, cervical intraepithelial neoplasia [CIN]) and invasive cervical neoplasia compared with patients without HIV infection.

AIS is much less common than its squamous counterpart, cervical intraepithelial neoplasia (CIN) grade 3 (previously called severe dysplasia or carcinoma in situ). In a multistate surveillance study in the United States from 2008 to 2015, 470 AIS cases were documented compared with 6587 CIN 3 cases . The median age of patients with AIS was older ...

Nov 8, 2022 · CIN grade – CIN 1 is a low-grade lesion that has a low potential for progression to malignancy and a high potential for regression , while CIN 2,3 is a high grade lesion that has a higher potential for progression and a lower potential for regression .

Jul 27, 2023 · Cervical intraepithelial neoplasia: Diagnostic excisional procedures; Cervical intraepithelial neoplasia: Management; Diagnostic imaging in pregnant and lactating patients; Invasive cervical cancer: Epidemiology, risk factors, clinical manifestations, and diagnosis; Invasive cervical cancer: Staging and evaluation of lymph nodes

Staging and primary management of invasive cervical cancer, as well as the approach to females treated for cervical cancer, are discussed separately.