The carotid body detects changes in the composition of arterial blood flowing through it, mainly the partial pressure of arterial oxygen, but also of carbon dioxide. It is also sensitive to changes in blood pH, and temperature.

Mar 17, 2024 · The carotid body is a small, ovoid, redish mass of tissue that lies posterior to the carotid bifurcation and close to the carotid sinus. It is covered by a fibrous capsule and composed of multiple lobules that are divided by septae.

Jul 25, 2023 · The carotid body is an extremely vascular organ and receives vascular supply via the internal and external carotid arteries. Two types of capillary beds are responsible for the perfusion of the organ.

Carotid body monitors the blood’s pH, pCO2, and pO2 and thereby modulates cardiovascular and respiratory function primarily through sympathetic tone. When the carotid body senses acidemia, hypercapnea, or hypoxia, autonomic firing leads to increased blood pressure, heart rate, and respiratory rate. The function of the carotid body is ...

The carotid body, an ellipsoid tissue mass located at the carotid bifurcation, is the main peripheral arterial chemoreceptor. It stimulates the ventilatory response, acting on central respiratory centres, in response to hypoxia, hypercapnia or reduced blood pH.

Jun 18, 2024 · The carotid body is located within the neck, and in close proximity to the carotid bifurcation. It is composed of a number of chemoreceptor cells and supporting matrix and detects changes in the composition of blood in the common carotid as it forms the internal and external carotid arteries.

The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O 2 and CO 2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to maintain homeostasis. This review examines the fundamental biology underlying CB chemoreceptor function, its contribution to integrated physiological responses, and ...

The carotid body is the main peripheral oxygen sensor involved in cardio-respiratory control under both normoxic and hypoxic conditions. This review focuses on data from newborn animals related to the involvement of the purinergic system in carotid body function during development.

The carotid body is located within the adventitia, posterior to the bifurcation of the carotid artery. Its role is to monitor blood gases and pH. Histologically, it is derived from cells originating from the neural crest ectoderm. A carotid body tumor (CBT) grows within the bifurcation and ultimately causes this to splay (Figure 36-23 A). The ...

Carotid Body Role: The Carotid Body acts as a sentinel, constantly monitoring the levels of oxygen, carbon dioxide, and pH in our blood. Its main function is to detect any imbalances, ensuring our body gets enough oxygen and maintaining the delicate acid-base balance necessary for cellular function.