Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders characterized by impaired cortisol synthesis. [1] [2] It results from the deficiency of one of the five enzymes required for the synthesis of cortisol in the adrenal cortex. [3]

Mar 22, 2024 · Congenital adrenal hyperplasia (CAH) is the medical name for a group of genetic conditions that affect the adrenal glands. The adrenal glands are a pair of walnut-sized organs above the kidneys. They make important hormones, including: Cortisol. This controls the body's response to illness or stress. Mineralocorticoids such as aldosterone.

Mar 2, 2018 · CAH refers to a group of genetic disorders that affect the adrenal glands. These glands sit on top of the kidneys and release hormones the body needs to function. CAH creates imbalances in these hormones, which cause a wide range …

Congenital adrenal hyperplasia (CAH) is a group of genetic disorders that affect your adrenal glands. These glands produce hormones your body needs to function properly. An imbalance in these hormones can cause symptoms affecting sexual development.

The prevalence of TARTs can be as high as 20% among children and between 50 and 80% in adults with classic CAH. An expert recommendation for boys with classic CAH is to perform testicular ultrasound starting at the age of 8 years and conduct follow-up scans every 2 years.

Dec 12, 2024 · Congenital Adrenal Hyperplasia (CAH) is a group of genetic disorders related to adrenal gland function that leads to hormonal imbalances. Explore its causes, symptoms, diagnosis, and treatment strategies.

Dec 19, 2024 · Today, the U.S. Food and Drug Administration approved Crenessity (crinecerfont) to be used together with glucocorticoids (steroids) to control androgen (a testosterone-like hormone) levels in...

Sep 19, 2018 · Healthcare professionals should inform all parents of pediatric patients with CAH (particularly girls with ambiguous genitalia) about surgical options, including delaying surgery until the child is older.

The form of CAH your baby has depends on which enzyme is not working. In the most common form of CAH, the enzyme 21-hydroxylase is not able to make enough of hormones called cortisol and aldosterone. This version is called CAH due to 21-hydroxylase deficiency (21-OHD).

Congenital adrenal hyperplasia due to 17α-hydroxylase deficiency is an uncommon form of congenital adrenal hyperplasia (CAH) resulting from a mutation in the gene CYP17A1, which produces the enzyme 17α-hydroxylase.