IgM: A negative cytomegalovirus (CMV) IgM result suggests that the patient is not experiencing acute or active infection. However, a negative result does not rule-out primary CMV infection.

CMV immunoglobulin G (IgG) antibodies are typically present for a longer duration and indicate a past or previous CMV infection. In contrast, CMV immunoglobulin M (IgM) antibodies are produced in response to a recent or active CMV infection and are transient in nature.

Serologic tests that detect CMV antibodies (IgM and IgG) are widely available from commercial laboratories. The enzyme-linked immunosorbent assay (ELISA) is the most common serologic test for measuring antibody to CMV.

Other names: CMV IgG and IgM, cytomegalovirus antibody. What are they used for? CMV tests help diagnose a current, reactivated, or past CMV infection in people at risk for health complications. Risk groups include: You are pregnant and have symptoms of a CMV infection. Why do I need a CMV test?

The enzyme-linked immunosorbent assay (ELISA) is the most common serologic test for measuring antibody to CMV. A positive test for CMV IgG indicates that a person was infected with CMV at some time during their life, but does not indicate when a person was infected.

Jun 20, 2023 · The main difference between CMV IgG and IgM is that IgG antibodies are the most common type of antibodies produced in response to a CMV infection, whereas IgM antibodies are the first type of antibodies to appear in the bloodstream during an active or recent CMV infection.

CMV serology aids in diagnosing CMV infection by detecting IgM antibodies, which indicate a recent infection, and IgG antibodies, which suggest past exposure. A positive IgM result combined with a rising IgG titer confirms an active infection.

By detecting IgM antibodies to cytomegalovirus, the cytomegalovirus IgM test plays a crucial role in diagnosing CMV infection. IgM antibodies are produced by the body’s immune system as a response to CMV infection, and their presence indicates a recent or active infection.

Positive CMV IgM results indicate a recent infection (primary, reactivation, or reinfection). IgM antibody responses in secondary (reactivation) CMV infections have been demonstrated in some CMV mononucleosis patients, a few pregnant women, and kidney and cardiac transplant patients.

Also, if your IgM and IgG levels are high, it may mean you have CMV. Your healthcare provider will likely give you the test again in 2 weeks to confirm the infection. If your IgG levels rise between the first and second test, that may mean you have an active infection.