Cyclic AMP-dependent transcription factor ATF-3 is a protein that, in humans, is encoded by the ATF3 gene. [5] Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of …

Dec 24, 2024 · ATF3 (Activating Transcription Factor 3) is a Protein Coding gene. Diseases associated with ATF3 include Hypospadias and Colorectal Cancer. Among its related pathways are Cellular responses to stimuli and PERK regulates gene expression.

Activating transcription factor 3 (ATF3) is a member of the ATF/cyclic AMP response element-binding (ATF/CREB) family of transcription factors. It is an adaptive-response gene that participates in cellular processes to adapt to extra- and/or ...

Sep 1, 2017 · Activating transcription factor 3 (ATF3) is a member of the ATF/cyclic adenosine monophosphate(cAMP)-response element binding protein (CREB) family of transcription factors. In response to stress stimuli, ATF3 forms dimers to activate or repress gene expression.

Activating transcription factor 3 (ATF3) gene encodes a member of the ATF family of transcription factors and is induced by various stress signals. All members of this family share the basic region-leucine zipper (bZip) DNA binding motif and bind to the consensus sequence TGACGTCA in vitro.

Aug 13, 2020 · Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays vital roles in modulating metabolism, immunity, and oncogenesis. ATF3 acts as a hub of the cellular adaptive-response network.

Activating transcription factor 3 (ATF3), a member of the ATF/CREB (cAMP response element-binding protein) family, plays a crucial role as cells respond to various stresses and damage.

Sep 28, 2015 · Activating transcription factor 3 (ATF3) is induced by inflammatory responses, cell death, cytokines and oxidative stress conditions. ATF3 is a negative regulator in the Toll-like receptor...

Nov 1, 2015 · Activating transcription factor 3 (ATF3) is an important transcriptional modulator that limits the inflammatory response by controlling the expression of a number of cytokines and chemokines. However, its role in modulating IFN responses remains poorly defined.

May 4, 2016 · Here, we employed ATF3 wild-type and knockout isogenic cell lines to carry out the first comprehensive analysis of global ATF3-binding profiles in the human genome under basal and stressed (DNA damage) conditions.