
ACVR2B - Wikipedia
Activin receptor type-2B is a protein that in humans is encoded by the ACVR2B gene. [5][6][7] ACVR2B is an activin type 2 receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.
ACVR2B Gene - GeneCards | AVR2B Protein | AVR2B Antibody
Dec 24, 2024 · ACVR2B (Activin A Receptor Type 2B) is a Protein Coding gene. Diseases associated with ACVR2B include Heterotaxy, Visceral, 4, Autosomal and Visceral Heterotaxy. Among its related pathways are Akt Signaling and Signaling by TGFB family members.
Activin type 2 receptors - Wikipedia
There are two activin type two receptors: ACVR2A and ACVR2B. Despite the large amount of processes that these ligands regulate, they all operate through essentially the same pathway: A ligand binds to a type 2 receptor, which recruits and trans-phosphorylates a type I receptor.
ACVR2B activin A receptor type 2B [ (human)] - National Center …
Feb 8, 2025 · Activin A inhibited signaling by BMP-6 and BMP-9 by competing for type 2 receptors ACVR2A and ACVR2B. We found that the AAAAA, AGGAG, and AGGGA haplotypes in ACVR2B were associated with susceptibility to Premature Ovarian Failure when they also had at least one CATAG haplotype in ADAMTS19.
Generation of activin receptor type IIB isoform-specific ... - PubMed
Activin receptor type IIB (Acvr2b) mediates multiple signals for transforming growth factor-beta (TGF-beta) family members, including Activin, Nodal, Bmp7, Gdf1, Gdf3, Myostatin (Gdf8), and Gdf11.
Q13705 - UniProt
May 16, 2006 · Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c).
ACVR2B activin A receptor type 2B [ Homo sapiens (human) ]
Title: MicroRNA-194 protects against chronic hepatitis B-related liver damage by promoting hepatocyte growth via ACVR2B. Study supported ACVR2B as the facilitator for clear cell kidney carcinoma (KIRC) development.
ACVR2B activin A receptor type 2B - NIH Genetic Testing …
Dec 10, 2024 · Clinical resource with information about ACVR2B, Genetic determinants of P wave duration and PR segment., Heterotaxy, visceral, 4, autosomal, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.
Entry - *602730 - ACTIVIN A RECEPTOR, TYPE IIB; ACVR2B
Jan 17, 2006 · ACVR2B contains an extracellular ligand binding domain, a transmembrane domain, and an intracellular serine/threonine kinase domain. Northern blot analysis of fetal tissues revealed that ACVR2B mRNAs are variably expressed in several tissues, with the highest level of expression in brain.
lncRNA ACVR2B-AS1 modulates thyroid cancer progression by
Mar 6, 2025 · Background lncRNAs are key regulators in thyroid cancer (TC). While lncRNA ACVR2B-AS1 has been proposed as a potential TC biomarker, its role remains underexplored. This study aims to clarify its clinical significance in TC and investigate its molecular mechanism. Materials and methods qRT-PCR was used to assess the expression of ACVR2B-AS1 in TC tissues and cell lines. Kaplan–Meier survival ...