Jan 3, 2007 · According to an FDA news release, the annual incidence of moderate to severe HIE is approximately 5000 to 9000 infants. No effective treatment was previously available, and support/symptomatic ...

Moderately severe infants with HIE exhibit lethargy, significant hypotonia and decreased deep tendon reflexes, decreased or absent primary reflexes (moro, suck, grasp), possible apnea, and a risk ...

Children with severe HIE have greater risk of cerebral palsy and mental retardation. The age at which the diagnosis of cerebral palsy can be confirmed is not until 5 years. Long-term follow-up is ...

Jan 8, 2019 · In a study of 160 full-term infants, two specific microRNAs (miR-374a-5p and miR-376c-3p) distinguished both infants with perinatal asphyxia (PA) and infants with HIE from healthy neonates.

Table 3. Recommended Inclusion/Exclusion Criteria for Hypothermia Treatment After HIE; Inclusion Criteria: Infants >36 weeks of age Infants who have been evaluated as moderate or severe HIE/Sarnat ...

Table 3. Recommended Inclusion/Exclusion Criteria for Hypothermia Treatment After HIE; Inclusion Criteria: Infants >36 weeks of age Infants who have been evaluated as moderate or severe HIE/Sarnat ...

Mar 11, 2025 · Significantly more cancer survivors had severe COVID-19 symptoms compared to the general population (17.9% vs 14.3%, P = .019). In addition, ...

May 29, 2024 · A new consensus guideline on the assessment and management of spasticity has been released. The American Academy of Physical Medicine and Rehabilitation (AAPM&R) guidance includes best practices ...

Jan 29, 2025 · A phase 2 trial of patients with moderate to severe psoriasis showed that 64% of those on high-dose treatment (40 mg twice daily) achieved PASI 75 at 12 weeks, whereas almost 39% achieved PASI 90 ...

Feb 25, 2025 · Preventative measures that exist today are based on risk stratification of more severe cardiac diseases, Skjelbred explained. “If you don’t have a known cardiovascular disease, you’re not ...