The carotid body detects changes in the composition of arterial blood flowing through it, mainly the partial pressure of arterial oxygen, but also of carbon dioxide. It is also sensitive to changes in blood pH, and temperature.

Jul 25, 2023 · The carotid body is an extremely vascular organ and receives vascular supply via the internal and external carotid arteries. Two types of capillary beds are responsible for the perfusion of the organ.

Mar 17, 2024 · The carotid body is a small, ovoid, redish mass of tissue that lies posterior to the carotid bifurcation and close to the carotid sinus. It is covered by a fibrous capsule and composed of multiple lobules that are divided by septae.

Carotid body monitors the blood’s pH, pCO2, and pO2 and thereby modulates cardiovascular and respiratory function primarily through sympathetic tone. When the carotid body senses acidemia, hypercapnea, or hypoxia, autonomic firing leads to increased blood pressure, heart rate, and respiratory rate. The function of the carotid body is ...

The carotid body (CB) is the main peripheral chemoreceptor for arterial respiratory gases O 2 and CO 2 and pH, eliciting reflex ventilatory, cardiovascular, and humoral responses to maintain homeostasis. This review examines the fundamental biology underlying CB chemoreceptor function, its contribution to integrated physiological responses, and ...

Jun 18, 2024 · The carotid body is located within the neck, and in close proximity to the carotid bifurcation. It is composed of a number of chemoreceptor cells and supporting matrix and detects changes in the composition of blood in the common carotid as it forms the internal and external carotid arteries.

Jul 24, 2023 · The carotid arteries are the primary vessels supplying blood to the brain and face.[1][2] The right common carotid artery (RCCA) originates in the neck from the brachiocephalic artery while the left common carotid artery (LCCA) arises in the thorax from the arch of the aorta.[3]

The carotid body, an ellipsoid tissue mass located at the carotid bifurcation, is the main peripheral arterial chemoreceptor. It stimulates the ventilatory response, acting on central respiratory centres, in response to hypoxia, hypercapnia or reduced blood pH.

Carotid Body Role: The Carotid Body acts as a sentinel, constantly monitoring the levels of oxygen, carbon dioxide, and pH in our blood. Its main function is to detect any imbalances, ensuring our body gets enough oxygen and maintaining the delicate acid-base balance necessary for cellular function.

Feb 10, 2020 · The carotid body (CB) is an arterial chemoreceptor organ located in the carotid bifurcation and has a well-recognized role in cardiorespiratory regulation. The CB contains neurosecretory sensory cells (glomus cells), which release transmitters in response to hypoxia, hypercapnia, and acidemia to act …