Western blotting and immunofluorescence staining were used to detect biomarker proteins of ferroptosis, inflammation, and AMPK/Nrf2/GPX4 signaling pathway proteins. Results: The results showed that ...

Department of Head and Neck Surgery, Sichuan Clinical Research Center for Cancer, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center University of Electronic Science and Technology of China, ...

Lou et al. (2021) discovered that Ginkgetin mediated ferroptosis in NSCLC by increasing iron concentration, promoting lipid peroxidation, inhibiting SLC7A11 and GPX4 expression, and reducing the ...

The mechanistic Target of Rapamycin complex 1 (mTORC1) senses intracellular amino acid levels through an intricate machinery, which includes the Rag GTPases, Ragulator and vacuolar ATPase (V-ATPase).