Create the best lineup on DraftKings for Sunday’s NFL Main Slate of games and take home the million-dollar first prize ...

Fred Warner will look to help inspire the San Francisco 49ers to a third successive sweep of the Seattle Seahawks on Sunday.

Kyle Shanahan praised San Francisco rookie wide receiver Ricky Pearsall's "impressive" comeback after being shot on Aug. 31 ...

The San Francisco 49ers boast one of the deepest WR groups in the league, but they could be ditching one of their best ...

Left tackle Trent Williams’ ankle and wrist injuries could force him to miss his first 49ers game this season Sunday against ...

The San Francisco 49ers have won back-to-back games since Brandon Aiyuk was lost for the season to a serious knee injury. San ...

The San Francisco 49ers are set to bolster their pass rush ahead of Sunday's game against the Seattle Seahawks. Head coach ...

NBC Sports San Francisco 49ers beat writer Jennifer Lee Chan gives the inside scoop on the Seattle Seahawks' next opponent.

The Seahawks are coming off a bye, having lost five of their past six games. The 49ers have won back-to-back games for the ...

Before their Week 11 matchup against the Seattle Seahawks, we'll be making our San Francisco 49ers bold predictions ...