On Friday, San Francisco 49ers head coach Kyle Shanahan addressed the media for the final time before the team’s Week 11 game ...

The San Francisco 49ers have won back-to-back games since Brandon Aiyuk was lost for the season to a serious knee injury. San ...

Kyle Shanahan praised San Francisco rookie wide receiver Ricky Pearsall's "impressive" comeback after being shot on Aug. 31 ...

The San Francisco 49ers are set to bolster their pass rush ahead of Sunday's game against the Seattle Seahawks. Head coach ...

Head coach Kyle Shanahan confirmed his initial injury update on Brandon Aiyuk during his Monday press conference call, stating the wideout suffered a torn ACL and MCL in the team's Week 7 matchup ...

The San Francisco 49ers are "worried" Brandon Aiyuk suffered an ACL injury during Sunday's 28-18 loss to the Kansas City Chiefs, head coach Kyle Shanahan told reporters postgame. Shanahan added ...

The 49ers fear that receiver Brandon Aiyuk has a torn anterior cruciate ligament, coach Kyle Shanahan said after the loss to the Chiefs. Aiyuk will undergo an MRI on Monday. "That's what it looks ...

San Francisco 49ers wide receiver Brandon Aiyuk exited Sunday's loss against ... After the 28–18 defeat, head coach Kyle Shanahan dropped a concerning update regarding the star wide receiver's ...

As the 49ers defeated the Tampa Bay Buccaneers in their Week 10 matchup, Kyle Shanahan gets real on Jauan Jennings' ...

The injuries have piled up for the hard-luck San Francisco 49ers following the season-ending setback to Brandon Aiyuk ... 49ers coach Kyle Shanahan said he called Aiyuk to talk to him about ...

Brandon Aiyuk suffered a torn ACL and MCL in Sunday's loss to the Chiefs, while Deebo Samuel is hospitalized with a form of pneumonia.

The San Francisco 49ers boast one of the deepest WR groups in the league, but they could be ditching one of their best ...