IgMs are produced by the immune system and play an important role in primary and adaptive humoral immune responses [1]. This class of antibodies ... In 2007 Gagnon and coworkers presented a three-step ...

Cell death is a process by which a cell's vital capacity is terminated. During an immune response, cells of the immune system cause the death of cells that are infected with microorganisms or are ...

Used clinically since the 1920s, corticosteroids interrupt multiple steps ... immune complexes. Therefore, pharmacologic manipulation of these cells may directly and indirectly impair the immune ...

Antibodies and related products are the fastest growing class of therapeutic agents. By analysing the regulatory approvals of IgG-based biotherapeutic agents in the past 10 years, we can gain ...

The collaboration AstraZeneca announced today is the first, and quite unexpected step of the pharma giant into the adeno-associated virus (AAV) gene therapy, vector discovery and product development.