Africa, Latin America, and certain regions of Asia face a heavy burden: diseases transmitted by insects, such as mosquitoes ...

Each of the underlying single-celled parasites — Trypanosoma brucei and its relatives — has one flagellum, a whiplike appendage that is essential for moving, infecting hosts and surviving in different ...

Millions of people worldwide are affected by African sleeping sickness, Chagas disease and other life-threatening infections ...

African sleeping sickness is a serious infection caused by a parasitic microbe called Trypanosoma brucei. Using an imaging ...

Trypanosoma cruzi; piperine; molecular hybridization; 1,2,4-triazole-3-thioether; human serum albumin ...

Using an innovative in vitro model of the blood-brain barrier, Dennis Grab of Johns Hopkins University and his colleagues found that Trypanosoma brucei gambiense requires calcium ions and cysteine ...