Down Syndrome, known as Trisomy 21, is a genetic disorder caused by an extra chromosome 21. It affects facial appearance, ...

The fragments also directly compromise synapses they encounter along the way, according to a preprint posted February 24 on bioRxiv. Specifically, tau fragments containing the microtubule binding ...

The M23 rebel group in the Democratic Republic of Congo reemerged from dormancy in 2022 and has since advanced across the country's troubled North Kivu province, sending hundreds of thousands of ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro proof-of-concept study. Down syndrome is caused by the presence of a third copy ...

This work advances our understanding of the trafficking defects caused by increased PCNT and has important implications for our understanding of the cellular basis of trisomy 21, a major hereditary ...